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Article

Identification of a preferred region for recombination and mutation in HIV-1 gag.

Virology - 1 Sept 2004

Dykes Carrie, Balakrishnan Mini, Planelles Vicente, Zhu Yonghong, Bambara Robert A, Demeter Lisa M

Abstract excerpt

We designed a cell culture-based system to test the hypothesis that recombination events during HIV-1 replication would be more frequent near the dimerization initiation sequence (DIS). A 459-bp region spanning the DIS through the 5'-end of gag was sequenced and analyzed to determine the frequency and distribution of crossover sites. We found a strong preference for recombination events occurring within a...

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PMID: 15302212
DOI: 10.1016/j.virol.2004.02.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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