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Article

A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.

The Journal of biological chemistry - 4 Dec 2009

Shen Wen, Gao Lu, Balakrishnan Mini, Bambara Robert A

Abstract excerpt

The co-packaged RNA genomes of human immunodeficiency virus-1 recombine at a high rate. Recombination can mix mutations to generate viruses that escape immune response. A cell-culture-based system was designed previously to map recombination events in a 459-bp region spanning the primer binding s...

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Identifiers

PMID: 19822521
DOI: 10.1074/jbc.M109.055368
PMCID: PMC2797159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19822521-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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