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Article

Identification of a major restriction in HIV-1 intersubtype recombination

14 Jun 2005

Abstract excerpt

Genetic recombination increases diversity in HIV-1 populations, thereby allowing variants to escape from host immunity or antiviral therapies. In addition to the currently described nine subtypes of HIV-1, many of the circulating strains are intersubtype recombinants. In this study, we determined the recombination rate between two HIV-1 subtype C viruses and between a subtype B virus and a subtype C virus during...

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PMID: 15956186
DOI: 10.1073/pnas.0502522102

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