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Article

The Nature of Human Immunodeficiency Virus Type 1 Strand Transfers

1 Oct 1998

Abstract excerpt

The diploid nature of human immunodeficiency virus type 1 (HIV-1) suggests that recombination serves a central function in virus replication and evolution. A system was developed to examine HIV-1 strand transfers, including the obligatory DNA primer strand transfers as well as recombinational crossovers during reverse transcription. Sequence heterogeneity between different strains of HIV-1 was exploited for...

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PMID: 9774465
DOI: 10.1074/jbc.273.43.28384

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