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Article

The origin of genetic diversity in HIV-1.

Virus research - 1 Nov 2012

Smyth Redmond P, Davenport Miles P, Mak Johnson

Abstract excerpt

One of the hallmarks of HIV infection is the rapid development of a genetically complex population (quasispecies) from an initially limited number of infectious particles. Genetic diversity remains one of the major obstacles to eradication of HIV. The viral quasispecies can respond rapidly to selective pressures, such as that imposed by the immune system and antiretroviral therapy, and frustrates vaccine design...

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Identifiers

PMID: 22728444
DOI: 10.1016/j.virusres.2012.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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