HIV-1 recombination: an experimental assay and a phylogenetic approach.

doi:10.1007/978-1-59745-170-3_7

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Article

HIV-1 recombination: an experimental assay and a phylogenetic approach.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Moore Michael D, Chin Mario P S, Hu Wei-Shau

Abstract excerpt

The generation of genetic diversity is a fundamental characteristic of HIV-1 replication, allowing the virus to successfully evade the immune response and antiviral therapies. Although mutations are the first step towards diversity, mixing of the mutations through the process of recombination increases the variation and allows for the faster establishment of advantageous strains within the viral population....

Topics

Cell Line
Genetic Variation
HIV-1
Humans
Phylogeny
Recombination, Genetic

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Identifiers

PMID: 19020820
DOI: 10.1007/978-1-59745-170-3_7
PMCID: PMC6785042

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