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High Rate of Recombination throughout the Human Immunodeficiency Virus Type 1 Genome

1 Feb 2000

Abstract excerpt

The diploid nature of human immunodeficiency virus type 1 (HIV-1) indicates that recombination serves a central function in virus replication and evolution. Previously, while examining the nature of obligatory primer strand transfers during reverse transcription, a high rate of recombination was observed at the ends of the viral genome within the viral long terminal repeats, prompting the following question: does...

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PMID: 10627533
DOI: 10.1128/jvi.74.3.1234-1240.2000

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