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Article

Selecting tagging SNPs for association studies using power calculations from genotype data.

Human heredity - 1 Jan 2004

Hu Xiaolan, Schrodi Steven J, Ross David A, Cargill Michele

Abstract excerpt

Recent studies have indicated that linkage disequilibrium (LD) between single nucleotide polymorphism (SNP) markers can be used to derive a reduced set of tagging SNPs (tSNPs) for genetic association studies. Previous strategies for identifying tSNPs have focused on LD measures or haplotype diversity, but the statistical power to detect disease-associated variants using tSNPs in genetic studies has not been fully...

Topics

Algorithms
Female
Gene Frequency
Genetic Predisposition to Disease
Genetic Testing
Genotype
Humans
Linkage Disequilibrium
Male
Models, Genetic
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Assessment

White People

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Identifiers

PMID: 15297809
DOI: 10.1159/000079246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15297809-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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