Article
Power analysis for genome-wide association studies.
BMC genetics - 28 Aug 2007
Klein Robert J
Abstract excerpt
BACKGROUND: Genome-wide association studies are a promising new tool for deciphering the genetics of complex diseases. To choose the proper sample size and genotyping platform for such studies, power calculations that take into account genetic model, tag SNP selection, and the population of interest are required. RESULTS: The power of genome-wide association studies can be computed using a set of tag SNPs and a...
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