Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploiting Hardy-Weinberg equilibrium for efficient screening of single SNP associations from case-control studies.

Human heredity - 1 Jan 2007

Chen Jinbo, Chatterjee Nilanjan

Abstract excerpt

In case-control studies, the assessment of the association between a binary disease outcome and a single nucleotide polymorphism (SNP) is often based on comparing the observed genotype distribution for the cases against that for the controls. In this article, we investigate an alternative analytic strategy in which the observed genotype frequencies of cases are compared against the expected genotype frequencies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Predisposition to Disease
Share to Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Statistical

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Selection Bias

Source

Identifiers

PMID: 17317968
DOI: 10.1159/000099996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploiting Hardy-Weinberg equilibrium for efficient screening of single SNP associations from case-control studies.PMID 17317968Read ↗

The power of independent types of genetic information to detect association in a case-control study design.Semantic proximity Read ↗

A likelihood ratio test of population Hardy-Weinberg equilibrium for case-control studies.Semantic proximity Read ↗

Analysis of epidemiologic studies of genetic effects and gene-environment interactions.Semantic proximity Read ↗

Testing Hardy-Weinberg proportions in a frequency-matched case-control genetic association study.Semantic proximity Read ↗

Assessing departure from Hardy-Weinberg equilibrium in the presence of disease association.Semantic proximity Read ↗

Statistical tests of genetic association for case-control study designs.Semantic proximity Read ↗

Genotype relative risks: methods for design and analysis of candidate-gene association studies.Semantic proximity Read ↗

Rare-variant association analysis: study designs and statistical tests.Semantic proximity Read ↗

A test for genetic association that incorporates information about deviation from Hardy-Weinberg proportions in cases.Semantic proximity Read ↗

A note on exact tests of Hardy-Weinberg equilibrium.Semantic proximity Read ↗

Leveraging Hardy–Weinberg disequilibrium for association testing in case-control studiesSemantic proximity Read ↗

Gene-based Hardy–Weinberg equilibrium test using genotype count data identifies novel cancer-related genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.