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Article

Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium.

American journal of human genetics - 1 Jan 2004

Carlson Christopher S, Eberle Michael A, Rieder Mark J, Yi Qian, Kruglyak Leonid, Nickerson Deborah A

Abstract excerpt

Common genetic polymorphisms may explain a portion of the heritable risk for common diseases. Within candidate genes, the number of common polymorphisms is finite, but direct assay of all existing common polymorphism is inefficient, because genotypes at many of these sites are strongly correlated. Thus, it is not necessary to assay all common variants if the patterns of allelic association between common variants...

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Identifiers

PMID: 14681826
DOI: 10.1086/381000
PMCID: PMC1181897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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