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Article

Statistical power of model selection strategies for genome-wide association studies.

PLoS genetics - 1 Jul 2009

Wu Zheyang, Zhao Hongyu

Abstract excerpt

Genome-wide association studies (GWAS) aim to identify genetic variants related to diseases by examining the associations between phenotypes and hundreds of thousands of genotyped markers. Because many genes are potentially involved in common diseases and a large number of markers are analyzed, it is crucial to devise an effective strategy to identify truly associated variants that have individual and/or...

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PMID: 19649321
DOI: 10.1371/journal.pgen.1000582
PMCID: PMC2712761

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