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Article

Kinetochores prevent repair of UV damage in Saccharomyces cerevisiae centromeres.

Molecular and cellular biology - 1 Aug 2004

Capiaghi Christoph, Ho The Vinh, Thoma Fritz

Abstract excerpt

Centromeres form specialized chromatin structures termed kinetochores which are required for accurate segregation of chromosomes. DNA lesions might disrupt protein-DNA interactions, thereby compromising segregation and genome stability. We show that yeast centromeres are heavily resistant to removal of UV-induced DNA lesions by two different repair systems, photolyase and nucleotide excision repair. Repair...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15282293
DOI: 10.1128/MCB.24.16.6907-6918.2004
PMCID: PMC479735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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