Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII.

doi:10.1091/mbc.e02-08-0533

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Article

Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII.

Molecular biology of the cell - 1 Nov 2003

Espelin Christopher W, Simons Kim T, Harrison Stephen C, Sorger Peter K

Abstract excerpt

Chromosome segregation at mitosis depends critically on the accurate assembly of kinetochores and their stable attachment to microtubules. Analysis of Saccharomyces cerevisiae kinetochores has shown that they are complex structures containing >/=50 protein components. Many of these yeast proteins have orthologs in animal cells, suggesting that key aspects of kinetochore structure have been conserved through...

Topics

Base Sequence
Chromosomes, Fungal
DNA-Binding Proteins
Kinetochores
Microtubules
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Sequence Analysis, DNA

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Identifiers

PMID: 13679521
DOI: 10.1091/mbc.e02-08-0533
PMCID: PMC266772

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