Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae.

doi:10.1073/pnas.89.19.8908

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Article

Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1992

Spencer F, Hieter P

Abstract excerpt

Cytological observations of animal cell mitoses have shown that the onset of anaphase is delayed when chromosome attachment to the spindle is spontaneously retarded or experimentally interrupted. This report demonstrates that a centromere DNA (CEN) mutation carried on a single chromosome can indu...

Topics

Alleles
Base Sequence
Cell Cycle
Centromere
Chromosomes, Bacterial
DNA, Fungal
Humans
Kinetics
Mitosis
Molecular Sequence Data
Mutagenesis
Saccharomyces cerevisiae
Sequence Deletion
Time Factors

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