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Article

A computational model of transmembrane integrin clustering.

Structure (London, England : 1993) - 1 Jun 2004

Gottschalk Kay-Eberhard, Kessler Horst

Abstract excerpt

The presented work describes a structural model for integrin homooligomerization, focusing on the transmembrane domains. The two noncovalently linked integrin subunits, alpha and beta, were previously shown to homodimerize or homotrimerize, respectively. Our work is based on published mutational work that induced homotrimerization of beta3 integrins. The mutations provided structural restraints for the creation...

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Identifiers

PMID: 15274930
DOI: 10.1016/j.str.2004.02.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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