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Article

Transmembrane and Juxtamembrane Structure of αL Integrin in Bicelles.

PloS one - 1 Jan 2013

Surya Wahyu, Li Yan, Millet Oscar, Diercks Tammo, Torres Jaume

Abstract excerpt

The accepted model for the interaction of α and β integrins in the transmembrane (TM) domain is based on the pair αIIbβ3. This involves the so-called outer and inner membrane association clasps (OMC and IMC, respectively). In the α chain, the OMC involves a GxxxG-like motif, whereas in the IMC a conserved juxtamembrane GFFKR motif experiences a backbone reversal that partially fills the void generated by TM...

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Identifiers

PMID: 24069290
DOI: 10.1371/journal.pone.0074281
PMCID: PMC3771934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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