Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals.

Clinical and experimental immunology - 1 Aug 2004

Cullup H, Middleton P G, Duggan G, Conn J S, Dickinson A M

Abstract excerpt

Cytokine production may be regulated by both genotypic (single nucleotide or tandem repeat polymorphisms) and non-genotypic factors relating to the environment and inherent biology (i.e. gender). Interleukin (IL)-1 is one of the body's most highly proinflammatory cytokines and is implicated in the pathophysiology of numerous diseases, but also in the maintenance of homeostasis in a number of tissues. The cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Interleukin-1

Share to Interleukin 1 Receptor Antagonist Protein

Share to Linkage Disequilibrium

Share to Sialoglycoproteins

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 15270852
DOI: 10.1111/j.1365-2249.2004.02531.x
PMCID: PMC1809100

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Environmental factors and not genotype influence the plasma level of interleukin-1 receptor antagonist in normal individuals.PMID 15270852Read ↗

Genetic control of IL-1beta bioactivity through differential regulation of the IL-1 receptor antagonist.Semantic proximity Read ↗

Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels.Semantic proximity Read ↗

The existence of gender difference in IL-1Ra gene polymorphism.Semantic proximity Read ↗

Genetic variation of the interleukin-1 family and nongenetic factors determining the interleukin-1 receptor antagonist phenotypes.Semantic proximity Read ↗

Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits.Semantic proximity Read ↗

Nonassociation of interleukin-1 receptor antagonist genotypes with bone mineral density, bone turnover status, and estrogen responsiveness in Korean postmenopausal women.Semantic proximity Read ↗

IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes.Semantic proximity Read ↗

Influence of interleukin-1 receptor antagonist gene polymorphism on disease.Semantic proximity Read ↗

Interleukin 1 gene polymorphism and susceptibility to disease.Semantic proximity Read ↗

The role of IL-1 gene cluster in longevity: a study in Italian population.Semantic proximity Read ↗

Physiologic role of interleukin-1 receptor antagonist.Semantic proximity Read ↗

Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.