Article
The existence of gender difference in IL-1Ra gene polymorphism.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Nov 2007
Bessler Hanna, Osovsky Micky, Beilin Benzion, Alcalay Yifat, Sirota Lea
Abstract excerpt
Interleukin-1beta (IL-1beta) and its endogenous antagonist IL-1 receptor antagonist (IL-1ra) play an important role in various inflammatory responses. The production of IL-1 and IL-1ra is regulated by genotypic and nongenotypic factors and is different between men and women. The aim of this study was to examine the existence of gender difference in the genetic polymorphism of these two cytokines. The genotypes of...
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