Article
An integrin-dependent role of pouch endoderm in hyoid cartilage development.
PLoS biology - 1 Sept 2004
Crump Justin Gage, Swartz Mary E, Kimmel Charles B
Abstract excerpt
Pharyngeal endoderm is essential for and can reprogram development of the head skeleton. Here we investigate the roles of specific endodermal structures in regulating craniofacial development. We have isolated an integrinalpha5 mutant in zebrafish that has region-specific losses of facial cartilages derived from hyoid neural crest cells. In addition, the cranial muscles that normally attach to the affected...
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