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Zebrafish Pax1a and Pax1b are required for pharyngeal pouch morphogenesis and ceratobranchial cartilage development.

Mechanisms of development - 1 Mar 2020

Liu Yu-Hsiu, Lin Tz-Chi, Hwang Sheng-Ping L

Abstract excerpt

Pharyngeal arches are derived from all three germ layers and molecular interactions among the tissue types are required for proper development of subsequent pharyngeal cartilages; however, the mechanisms underlying this process are not fully described. Here we report that in zebrafish, Pax1a and Pax1b have overlapping and essential functions in pharyngeal pouch morphogenesis and subsequent ceratobranchial...

Topics

Animals
Branchial Region
Cartilage
Endoderm
Gene Expression Regulation, Developmental
Morphogenesis
Mutation
Paired Box Transcription Factors
Signal Transduction
Zebrafish
Zebrafish Proteins

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PMID: 32061871
DOI: 10.1016/j.mod.2020.103598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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