Article
Foxi1 promotes late-stage pharyngeal pouch morphogenesis through ectodermal Wnt4a activation.
Developmental biology - 1 Sept 2018
Jin Sil, O Jiyun, Stellabotte Frank, Choe Chong Pyo
Abstract excerpt
The pharyngeal pouches are a series of epithelial outgrowths of the foregut endoderm. Pharyngeal pouches segment precursors of the vertebrate face into pharyngeal arches and pattern the facial skeleton. These pouches fail to develop normally in zebrafish foxi1 mutants, yet the role Foxi1 plays in pouch development remains to be determined. Here we show that ectodermal Foxi1 acts downstream of Fgf8a during the...
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