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Article

Zebrafish pou5f1/pou2, homolog of mammalian Oct4, functions in the endoderm specification cascade.

Current biology : CB - 6 Jan 2004

Lunde Karen, Belting Heinz-Georg, Driever Wolfgang

Abstract excerpt

pou5f1, also known as Oct4, is required to establish the pluripotent cell population necessary for embryogenesis in mouse. Additional roles during development, including endoderm formation, have been proposed. In zebrafish, the zygotic pou5f1/pou2 mutant spiel ohne grenzen (spg) shows neural plate patterning defects and reduced endoderm at the tailbud stage. To investigate the function of maternal and early...

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Identifiers

PMID: 14711414
DOI: 10.1016/j.cub.2003.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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