Article

A single-cell atlas of pig gastrulation as a resource for comparative embryology

2023-09-02

Abstract excerpt

Early mammalian gastrulation’s cell-fate decisions are poorly understood due to difficulties obtaining non-rodent embryos. The bilaminar disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation. Here we present a single-cell transcriptomic atlas of pig gastrulation, revealing cell-fate emergence dynamics, as well as conserved and divergent gene programs governing early porcine, prim...

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Literature Corpus work: e7ef8cbf-5c19-57ab-8eb1-c4d470bbad15
DOI: 10.1101/2023.08.31.555712

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