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Article

Cell context-specific effects of the beta-tubulin glycylation domain on assembly and size of microtubular organelles.

Molecular biology of the cell - 1 Sept 2004

Thazhath Rupal, Jerka-Dziadosz Maria, Duan Jianming, Wloga Dorota, Gorovsky Martin A, Frankel Joseph, Gaertig Jacek

Abstract excerpt

Tubulin glycylation is a posttranslational modification found in cells with cilia or flagella. The ciliate Tetrahymena has glycylation on ciliary and cortical microtubules. We showed previously that mutating three glycylation sites on beta-tubulin produces immotile 9 + 0 axonemes and inhibits cytokinesis. Here, we use an inducible glycylation domain mutation and epitope tagging to evaluate the potential of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15254268
DOI: 10.1091/mbc.e04-03-0247
PMCID: PMC515347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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