Article
Katanin regulates dynamics of microtubules and biogenesis of motile cilia.
The Journal of cell biology - 10 Sept 2007
Sharma Neeraj, Bryant Jessica, Wloga Dorota, Donaldson Rachel, Davis Richard C, Jerka-Dziadosz Maria, Gaertig Jacek
Abstract excerpt
The in vivo significance of microtubule severing and the mechanisms governing its spatial regulation are not well understood. In Tetrahymena, a cell type with elaborate microtubule arrays, we engineered null mutations in subunits of the microtubule-severing complex, katanin. We show that katanin...
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