Article
Mutations of tubulin glycylation sites reveal cross-talk between the C termini of alpha- and beta-tubulin and affect the ciliary matrix in Tetrahymena.
The Journal of biological chemistry - 7 Jan 2005
Redeker Virginie, Levilliers Nicolette, Vinolo Emilie, Rossier Jean, Jaillard Danielle, Burnette Dylan, Gaertig Jacek, Bré Marie-Hélène
Abstract excerpt
Two types of polymeric post-translational modifications of alpha/beta-tubulin, glycylation and glutamylation, occur widely in cilia and flagella. Their respective cellular functions are poorly understood. Mass spectrometry and immunoblotting showed that two closely related species, the ciliates Tetrahymena and Paramecium, have dramatically different compositions of tubulin post-translational modifications in...
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