Article

Glutamylation imbalance leads to photoreceptor cell degeneration

2024-04-13

Abstract excerpt

The stereotypic structure of microtubules, assembled from conserved α/β-tubulin dimers is subject to a complex diversity of Post-translational Modifications (PTMs). PTMs are predicted to fine-tune microtubule properties and interactions with other proteins, thus allowing microtubules to perform specific functions. Cilia accumulate several types of tubulin PTMs, such as polyglutamylation, polyglycylation, detyrosin...

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Literature Corpus work: 6e350685-75e5-5588-bc73-4dbdf86deed7
DOI: 10.1101/2024.04.09.588666

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