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Article

Kinesin-13 regulates the quantity and quality of tubulin inside cilia.

Molecular biology of the cell - 1 Feb 2015

Vasudevan Krishna Kumar, Jiang Yu-Yang, Lechtreck Karl F, Kushida Yasuharu, Alford Lea M, Sale Winfield S, Hennessey Todd, Gaertig Jacek

Abstract excerpt

Kinesin-13, an end depolymerizer of cytoplasmic and spindle microtubules, also affects the length of cilia. However, in different models, depletion of kinesin-13 either lengthens or shortens cilia, and therefore the exact function of kinesin-13 in cilia remains unclear. We generated null mutations of all kinesin-13 paralogues in the ciliate Tetrahymena. One of the paralogues, Kin13Ap, localizes to the nuclei and...

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Identifiers

PMID: 25501369
DOI: 10.1091/mbc.E14-09-1354
PMCID: PMC4310739

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ATAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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