Article
Point mutation at codon 12 of the c-Ha-ras gene in human gastric cancers.
Journal of Korean medical science - 1 Jun 1992
Koh E H, Chung H C, Lee K B, Han E K, Oh S H, Min J S, Choi E M, Youn J K, Kim B S
Abstract excerpt
The molecular mechanisms of the carcinogenic process of gastric cancer have not been fully understood yet. In order to know whether c-Ha-ras gene is being involved in the process of gastric carcinogenesis, 8 gastric cancer cell lines, 8 cases of gastric cancer and same number of adjacent dysplasia were analyzed for the presence of mutation at codon 12, 13 and 61 of the c-Ha-ras gene by using polymerase chain...
Topics
- Base Sequence
- Codon
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Stomach Neoplasms
