Article
Infrequent point mutations of ras oncogenes in gastric cancers.
Gastroenterology - 1 Apr 1990
Nanus D M, Kelsen D P, Mentle I R, Altorki N, Albino A P
Abstract excerpt
Adenocarcinomas of the proximal and distal stomach have significant clinical and biological differences. A study was undertaken to determine if a difference in the incidence of mutated ras oncogenes exists between proximal (gastroesophageal junction or cardia) and distal (body or antrum) gastric tumors, and to assess the overall incidence in gastric cancers from non-Asian patients. Deoxyribonucleic acid from 28...
Topics
- Adenocarcinoma
- Base Sequence
- DNA Mutational Analysis
- DNA, Neoplasm
- Esophagogastric Junction
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
