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Article

Point mutation of c-Ki-ras oncogene in gastric adenoma and adenocarcinoma with tubular differentiation.

Japanese journal of cancer research : Gann - 1 Mar 1991

Kihana T, Tsuda H, Hirota T, Shimosato Y, Sakamoto H, Terada M, Hirohashi S

Abstract excerpt

The presence of point mutation at codons 12, 13 and 61 of the c-Ki-ras oncogene was investigated in 7 cases of gastric adenoma and 35 cases of gastric adenocarcinoma using DNA samples from formalin-fixed and paraffin-embedded tissues. Oligonucleotides encompassing the three codons were amplified by using the polymerase chain reaction (PCR), and then examined for point mutation by the selective oligonucleotide...

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Identifiers

PMID: 1902452
DOI: 10.1111/j.1349-7006.1991.tb01847.x
PMCID: PMC5918400

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Source receipt: pubmed, retrieved 7 Sept 2026.

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