Article
[Point mutation of c-Ha-ras oncogene in oral cancers].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology - 1 Nov 1991
Liu X F
Abstract excerpt
After sub-sequence of c-Ha-ras oncogene in 11 Chinese oral cancers was amplified with in vitro DNA amplification technique, G----T mutation of c-Ha-ras oncogene at codon 12 was detected by specific mutated oligonucleotide probe, resulting in point mutation of c-Ha-ras oncogene at codon 12 in 4 out of 11 oral cancers which shows that c-Ha-ras oncogene is one of the genes associated with the development and...
Topics
- Base Sequence
- Codon
- Gene Amplification
- Genes, ras
- Humans
- Molecular Sequence Data
- Mouth Neoplasms
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
