Article
Infrequent ras mutation in human stomach cancers.
Japanese journal of cancer research : Gann - 1 Feb 1993
Koshiba M, Ogawa O, Habuchi T, Hamazaki S, Shimada T, Takahashi R, Sugiyama T
Abstract excerpt
Mutations of ras oncogenes in 37 human stomach cancers and 13 adenomas were investigated with regard to the histological phenotypes using polymerase chain reaction (PCR), allele-specific oligonucleotide hybridization and/or direct sequencing of the PCR products. The ras mutation was found only in one case (2.7%), the histology of which was poorly differentiated adenocarcinoma. We found no mutation in stomach...
Topics
- Adenocarcinoma
- Adenoma
- Adult
- Aged
- Aged, 80 and over
- Female
- Genes, ras
- Humans
- Male
- Middle Aged
- Phenotype
- Point Mutation