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Focal adhesion kinase (FAK): emerging target for drug-resistant malignant tumors

20 Feb 2025

Abstract excerpt

Malignant tumors associated with drug resistance present a significant challenge for clinicians and drug developers. Mutations and alterations within the tumor microenvironment frequently drive cancer cell invasion and metastasis. Despite identifying numerous molecular targets and lead compounds, achieving sustained efficacy remains challenging due to the rapid mutation rates and the emergence of resistance....

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PMID: 39976799
DOI: 10.1007/s11033-025-10296-7

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