Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and Development

1 Sept 2011

Abstract excerpt

Recent studies connect the FAK and Wnt/β-catenin signaling pathways, both which promote cancer when aberrantly activated in mammalian cells. Over-stimulation of either Wnt/β-catenin or FAK activities was independently shown to promote numerous types of human cancers, including colon, breast, prostate and ovary. Observations in different model systems suggest a complex and dynamic cross-talk between these two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21707509
DOI: 10.2174/187152011796817673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FAK and WNT Signaling: The Meeting of Two Pathways in Cancer and DevelopmentPMID 21707509Read ↗

The Crosstalk between FAK and Wnt Signaling Pathways in Cancer and Its Therapeutic ImplicationSemantic proximity Read ↗

Understanding the Roles of FAK in CancerSemantic proximity Read ↗

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42.Semantic proximity Read ↗

Control of motile and invasive cell phenotypes by focal adhesion kinase.Semantic proximity Read ↗

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer DevelopmentSemantic proximity Read ↗

New Insights on the Nuclear Functions and Targeting of FAK in CancerSemantic proximity Read ↗

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and TherapySemantic proximity Read ↗

Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc SignalingSemantic proximity Read ↗

FAK regulates biological processes important for the pathogenesis of cancer.Semantic proximity Read ↗

Focal adhesion kinase and cancer.Semantic proximity Read ↗

Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate.Semantic proximity Read ↗

OMICs based identification of the mechanisms that underpin FAK's regulation of gene expressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.