Article
FAK regulates biological processes important for the pathogenesis of cancer.
Cancer metastasis reviews - 1 Dec 2003
Gabarra-Niecko Veronica, Schaller Michael D, Dunty Jill M
Abstract excerpt
Since its initial discovery as a substrate and binding partner for the Src oncogene, a role for the focal adhesion kinase (FAK) in cancer has been speculated. In this review the clinical evidence correlating FAK overexpression with cancer and the experimental evidence demonstrating that FAK can control some phenotypes associated with cancer will be discussed. In addition, the emerging theme of interactions...
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