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Article

Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12.

BMC genetics - 6 Jul 2004

Schmidt Silke, Scott William K, Postel Eric A, Agarwal Anita, Hauser Elizabeth R, De La Paz Monica A, Gilbert John R, Weeks Daniel E, Gorin Michael B, Haines Jonathan L, Pericak-Vance Margaret A

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a complex disorder that is responsible for the majority of central vision loss in older adults living in developed countries. Phenotypic and genetic heterogeneity complicate the analysis of genome-wide scans for AMD susceptibility loci. The ordered subset analysis (OSA) method is an approach for reducing heterogeneity, increasing statistical power for...

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Identifiers

PMID: 15238159
DOI: 10.1186/1471-2156-5-18
PMCID: PMC481059

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DBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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