Article
A discordant sib-pair linkage analysis of age-related macular degeneration.
Ophthalmic genetics - 1 Jun 2005
Santangelo Susan L, Yen Chen-Hsing, Haddad Stephen, Fagerness Jesen, Huang Christine, Seddon Johanna M
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of visual impairment and blindness among older adults in the United States and throughout the developed world. Etiological research implicates both genetic and environmental components. Our prior genome scan in 511 affected sib-pairs and other relative pairs identified significant or suggestive linkage signals on chromosomes 1, 2, 3, 6, 8,...
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