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Article

Ordered subset analysis supports a glaucoma locus at GLC1I on chromosome 15 in families with earlier adult age at diagnosis.

Experimental eye research - 1 Jun 2006

Woodroffe Abigail, Krafchak Charles M, Fuse Nobuo, Lichter Paul R, Moroi Sayoko E, Schertzer Robert, Downs Catherine A, Duren William L, Boehnke Michael, Richards Julia E

Abstract excerpt

Open angle glaucoma (OAG) is a complex disorder with varying etiologies due to multiple genes and environmental effects. This genetic heterogeneity can confound efforts to map loci. Increased homogeneity in a sample can be achieved using either ordered subset analysis (OSA) which groups families, or individual OSA (IOSA), which groups individuals based on disease related covariates. Recently, GLC1I was mapped to...

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Identifiers

PMID: 16298363
DOI: 10.1016/j.exer.2005.10.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Ordered subset analysis supports a glaucoma locus at GLC1I on chromosome 15 in families with earlier adult age at diagnosis.PMID 16298363Read ↗

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