Article
Meta-analysis of genome scans of age-related macular degeneration.
Human molecular genetics - 1 Aug 2005
Fisher Sheila A, Abecasis Goncalo R, Yashar Beverly M, Zareparsi Sepideh, Swaroop Anand, Iyengar Sudha K, Klein Barbara E K, Klein Ronald, Lee Kristine E, Majewski Jacek, Schultz Dennis W, Klein Michael L, Seddon Johanna M, Santangelo Susan L, Weeks Daniel E, Conley Yvette P, Mah Tammy S, Schmidt Silke, Haines Jonathan L, Pericak-Vance Margaret A, Gorin Michael B, Schulz Heidi L, Pardi Fabio, Lewis Cathryn M, Weber Bernhard H F
Abstract excerpt
A genetic contribution to the development of age-related macular degeneration (AMD) is well established. Several genome-wide linkage studies have identified a number of putative susceptibility loci for AMD but only a few of these regions have been replicated in independent studies. Here, we perform a meta-analysis of six AMD genome screens using the genome-scan meta-analysis method, which allows linkage results...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.