Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits.

Obesity (Silver Spring, Md.) - 1 Oct 2008

Meigs James B, Manning Alisa K, Dupuis Josée, Liu Chunyu, Florez Jose C, Cupples L Adrienne

Abstract excerpt

Phenotypic heterogeneity complicates detection of genomic loci predisposing to type 2 diabetes, potentially obscuring or unmasking specific loci. We conducted ordered-subsets linkage analyses (OSAs) for diabetes-related quantitative traits (fasting insulin and glucose, hemoglobin A1c (HbA1c), and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Body Size
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 19

Share to Diabetes Mellitus

Share to Genetic Heterogeneity

Share to Glycated Hemoglobin

Share to Lod Score

Source

Open in PubMed Open full text

Identifiers

PMID: 18719643
DOI: 10.1038/oby.2008.354
PMCID: PMC3747653

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18719643-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ordered stratification to reduce heterogeneity in linkage to diabetes-related quantitative traits.PMID 18719643Read ↗

Ordered subset analysis in genetic linkage mapping of complex traits.Semantic proximity Read ↗

Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs.Semantic proximity Read ↗

Ordered subset analysis for case-control studies.Semantic proximity Read ↗

Ordered subset linkage analysis supports a susceptibility locus for age-related macular degeneration on chromosome 16p12.Semantic proximity Read ↗

Ordered-subset analysis (OSA) for family-based association mapping of complex traits.Semantic proximity Read ↗

Application of an ordered subset analysis approach to the genetics of alcoholism.Semantic proximity Read ↗

Interpreting analyses of continuous covariates in affected sibling pair linkage studies.Semantic proximity Read ↗

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11.Semantic proximity Read ↗

A genome-wide scan in type 2 diabetes mellitus provides independent replication of a susceptibility locus on 18p11 and suggests the existence of novel Loci on 2q12 and 19q13.Semantic proximity Read ↗

Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q.Semantic proximity Read ↗

Early adult-onset POAG linked to 15q11-13 using ordered subset analysis.Semantic proximity Read ↗

Genome-wide and Ordered-Subset linkage analyses provide support for autism loci on 17q and 19p with evidence of phenotypic and interlocus genetic correlates.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.