Article
Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts.
Molecular and cellular biology - 1 Jul 2004
Carroll Kristina L, Pradhan Dennis A, Granek Josh A, Clarke Neil D, Corden Jeffry L
Abstract excerpt
RNA polymerase II (Pol II) termination is triggered by sequences present in the nascent transcript. Termination of pre-mRNA transcription is coupled to recognition of cis-acting sequences that direct cleavage and polyadenylation of the pre-mRNA. Termination of nonpolyadenylated [non-poly(A)] Pol II transcripts in Saccharomyces cerevisiae requires the RNA-binding proteins Nrd1 and Nab3. We have used a mutational...
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