Article
A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formation.
Molecular cell - 28 Oct 2005
Sheldon Kathryn E, Mauger David M, Arndt Karen M
Abstract excerpt
RNA synthesis and processing are coordinated by proteins that associate with RNA polymerase II (pol II) during transcription elongation. The yeast Paf1 complex interacts with RNA pol II and mediates histone modifications during elongation. To elucidate the functions of this complex, we isolated missense mutations in the gene encoding the Rtf1 subunit and used them to identify functionally interacting proteins. We...
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