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Article

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.

Molecular cell - 9 Oct 2009

Rondón Ana G, Mischo Hannah E, Kawauchi Junya, Proudfoot Nick J

Abstract excerpt

Transcription termination of RNA polymerase II (Pol II) on protein-coding genes in S. cerevisiae relies on pA site recognition by 3' end processing factors. Here we demonstrate the existence of two alternative termination mechanisms that rescue polymerases failing to disengage from the template at pA sites. One of these fail-safe mechanisms is mediated by the NRD complex, similar to termination of short noncoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19818712
DOI: 10.1016/j.molcel.2009.07.028
PMCID: PMC2779338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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