Article
cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II.
Molecular and cellular biology - 1 Apr 2006
Steinmetz Eric J, Ng Sarah B H, Cloute Joseph P, Brow David A
Abstract excerpt
Most eukaryotic genes are transcribed by RNA polymerase II (Pol II), including those that produce mRNAs and many noncoding functional RNAs. Proper expression of these genes requires efficient termination by Pol II to avoid transcriptional interference and synthesis of extended, nonfunctional RNAs. We previously described a pathway for yeast Pol II termination that involves recognition of an element in the nascent...
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