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Article

Termination of cryptic unstable transcripts is directed by yeast RNA-binding proteins Nrd1 and Nab3.

Molecular cell - 15 Sept 2006

Arigo John T, Eyler Daniel E, Carroll Kristina L, Corden Jeffry L

Abstract excerpt

Studies of yeast transcription have revealed the widespread distribution of intergenic RNA polymerase II transcripts. These cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome. Yeast RNA binding proteins Nrd1 and Nab3 direct termination of sn/snoRNAs and recently have also been implicated in premature transcription termination of the NRD1 gene. In this paper, we show that Nrd1 and Nab3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16973436
DOI: 10.1016/j.molcel.2006.07.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Termination of cryptic unstable transcripts is directed by yeast RNA-binding proteins Nrd1 and Nab3.PMID 16973436Read ↗

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A genetic screen for terminator function in yeast identifies a role for a new functional domain in termination factor Nab3.Semantic proximity Read ↗

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The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome.Semantic proximity Read ↗

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