Article
Experimental studies of deleterious mutation in Saccharomyces cerevisiae.
Research in microbiology - 1 Jun 2004
Korona Ryszard
Abstract excerpt
Yeast has proven to be a very useful model organism for studying eukaryotic cell functions. Its applicability for population and quantitative genetics is less well known. Among its advantages is the ease of screening for mutants. The present paper reviews experiments aimed at estimating the parameters of spontaneous mutations deleterious to fitness. The rate of deleterious mutation was found to be moderately...
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