Mutations in yeast are deleterious on average regardless of the degree of adaptation to the testing environment.

Abstract excerpt

The role of spontaneous mutations in evolution depends on the distribution of their effects on fitness. Despite a general consensus that new mutations are deleterious on average, a handful of mutation accumulation experiments in diverse organisms instead suggest that beneficial and deleterious mu...

Topics

• Saccharomyces cerevisiae
• Mutation
• Genetic Fitness
• Adaptation, Physiological
• Genotype
• Environment