Article
The ETS transcription factor GABPalpha is essential for early embryogenesis.
Molecular and cellular biology - 1 Jul 2004
Ristevski Sika, O'Leary Debra A, Thornell Anders P, Owen Michael J, Kola Ismail, Hertzog Paul J
Abstract excerpt
The ETS transcription factor complex GABP consists of the GABPalpha protein, containing an ETS DNA binding domain, and an unrelated GABPbeta protein, containing a transactivation domain and nuclear localization signal. GABP has been shown in vitro to regulate the expression of nuclear genes involved in mitochondrial respiration and neuromuscular signaling. We investigated the in vivo function of GABP by...
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